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Enzymology & Inhibitor Characterization

Enzymology & Inhibitor Characterization is a key to understand SAR and mechanism of inhibition. After rapid progress in the last a few decades, enzymology has become a relatively mature area now. Our well-trained and highly experienced enzymologists have worked on various enzymes for many years in both academic and industry settings. We provide following services and contract research.

  • basic properties of an enzyme: Km, Kcat and Vmax
  • inhibitor characterization,
    IC50 and Ki determination
    mode of inhibition ( competitive, non-competitive or un-competitive)
  • inhibitor binding to enzyme: Kd, kon and koff
  • slow and tight binding inhibitors
    mutation
    competition
    chemical labeling
    NMR
    co-cystalization
  • assay design, development and execution
    protease
    polymerase
    dehydrogenase
    inhibitor binding
    more
  • complicate and difficult projects

We guarantee publication quality results. Please email us your project or problems.
We will send you a brief summary and then call you for further discussion.